Specifications include, but are not limited to: SYSTEM AND OPERATIONAL REQUIREMENTS - utilizes an absolute particle counting technique, such as nanoparticle tracking analysis with no need for frequent calibrations; capable of characterization of nanomaterials in aqueous solutions in the size range of 10 – 1000 nm and concentrations of approximately 100 particles/milliliter; capable of light scattering and fluorescence detection of particles, including a method to reliably collect data during photobleaching; able to detect and count fluorescent molecules using a green laser to excite particles at around 490 nm within housing to limit laser exposure by the user; system is capable of interchanging laser modules allowing for different excitation sources (potential future modules: 405 nm, 532 nm, and 642 nm); capable of analyzing sample volumes as small as 250 µl