The Topic-Specific Centers of Excellence (COE) will serve as statewide Clinical Education programs addressing one of the designated clinical topics: HIV Primary Care and Prevention, Sexual Health, or Hepatis C Virus/Drug User Health. Centers will utilize Specific/ Measurable/ Achievable/ Relevant/ Time-Bound (SMART) goals to plan, implement, and evaluate clinical education activities. The funded applicants will deliver a mix of live in-person and virtual events, including asynchronous online clinical education programs, develop brief podcasts and videos, convene an annual conference, and prepare other print and digital clinical education tools. The intended audience for the activities of the Clinical Education Initiative (CEI) include Medical Doctors (MDs), Doctors of Osteopathy (DOs), physician assistants (PAs), nurse practitioners (NPs), registered nurses (RNs), and other public health staff working in sexual health/Sexually Transmitted Infections (STI) clinics.