Specifications include, but are not limited to: 2.1.Tandem Quadrupole Analyzer 2.1.1.The quadrupole analyzers (MS1 and MS2) WITH A M/Z OR 2-2048 AMU RANGE. 2.1.2.Scan Speed of up to 20,000 Da/sec 2.1.3.Capability of switching between MS and MS/MS in a single acquisition 2.1.4.Capability of positive/negative polarity switching to allow for a long list of compounds inm a single acquisition. 2.1.5.Ability to preform alternating full can data acquisition and quantitative MRM acquisition in the run with MS to MS/MS switching. 2.1.6.Provide in to 32,000+ MRM channels in a single acquisition. 2.2 Z Spray Interface 2.2.1 Equipped with a dual mode (ESI) Electro Spray Ionization/(API) Atmospheric Pressure Ionization source. The source should be easily removable for cleaning without the need for tools or breaking the vacuum. 2.3 On-Board Infusion System 2.3.1The instrument must be equipped with a software controlled on-board infusion system capable of delivering reference solutions from buil.t-in vial locations for either direct or combined into an LC flow infusion into the source. 2.4 Collision Cell 2.4.1 The instrument should be equipped with a collision cell which allows the collision energy and gas pressure to be adjusted with programmable software control and automatically recorded and appended to the relevant data file during data acquisition.