Please note: This is a Sole Source Notification. The Department of Health and Senior Services (DHSS) has an ongoing need for the methamphetamine precursor database system called National Precursor Log Exchange (NPLEx). DHSS has utilized the NPLEx system since 2011 to track sales of pseudoephedrine products so that sales of excess products for the use of manufacturing methamphetamine would be restricted. DHSS requires continued use the NPLEx system for the following reasons: the database is provided at no cost to the State of Missouri and to provide consistency through their partnership with the Consumer Healthcare Product Association, the National Association of Drug Diversion Investigators, and the 35 states using the system. Appriss Insights LLC is the sole licensed operator of NPLEx. According to RSMO 34.044, a single feasible source can be utilized when the product/service requirement is proprietary and only available from a single provider. As a result, this represents a proprietary requirement that meets the criteria of a single feasible source under RSMo 34.044 and the State is pursuing this acquisition as a Single Feasible Source.